Analytical Data
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Gene name
TMED10
- Application
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Alternative Names
TMED10；TMP21；Transmembrane emp24 domain-containing Protein 10
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P49755
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Expression Region
1-219aa
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AA Sequence
MSGLSGPPARRGPFPLALLLLFLLGPRLVLAISFHLPINSRKCLREEIHKDLLVTGAYEISDQSGGAGGLRSHLKITDSAGHILYSKEDATKGKFAFTTEDYDMFEVCFESKGTGRIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMFCLIGLATWQVFYLRRFFKAKKLIE
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TMED10, a member of the transmembrane emp24 domain (TMED) protein family, plays a crucial role in the intracellular transport and processing of glycoproteins. Researchers have identified TMED10 as a key component in the endoplasmic reticulum-Golgi intermediate compartment, which is essential for the efficient trafficking of proteins between the endoplasmic reticulum and the Golgi apparatus. Its involvement in vesicular transport mechanisms has intrigued scientists, given its potential implications in cellular functions and pathologies. Furthermore, alterations in TMED10 expression and function have been linked to various diseases, including cancer and neurodegenerative disorders, highlighting its significance in maintaining cellular homeostasis. The study of recombinant TMED10 protein has emerged as a critical area of research, aiming to elucidate its structural characteristics, functional properties, and interactions with other cellular components. By producing and analyzing recombinant TMED10, researchers hope to uncover insights into the molecular mechanisms underlying its role in protein transport and its contribution to disease processes, which could eventually lead to the development of novel therapeutic strategies targeting diseases associated with TMED10 dysregulation.
