Analytical Data
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基因名
ANGPTL1
- Application
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别名
ANG 3; ANG-3; ANG3; Angioarrestin; Angiopoietin 3; Angiopoietin like 1; Angiopoietin like Protein 1
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O95841
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表达区间
24-491aa
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氨基酸序列
GQFKIKKINQRRYPRATDGKEEAKKCAYTFLVPEQRITGPICVNTKGQDASTIKDMITRMDLENLKDVLSRQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDTHVSPPLVQVVPQHIPNSQQYTPGLLGGNEIQRDPGYPRDLMPPPDLATSPTKSPFKIPPVTFINEGPFKDCQQAKEAGHSVSGIYMIKPENSNGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNIDGEYWLGLENIYMLSNQDNYKLLIELEDWSDKKVYAEYSSFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKHQDGIFWAEYRGGSYSLRAVQMMIKPID
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分子量
77.22 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ANGPTL1 (Angiopoietin-like protein 1) is a member of the angiopoietin-like family, playing a crucial role in various physiological processes, including angiogenesis, metabolism, and inflammation. Research has increasingly focused on ANGPTL1 due to its implications in cardiovascular diseases and metabolic disorders. It has been shown to modulate lipid metabolism by inhibiting lipoprotein lipase (LPL), which impacts triglyceride levels and energy homeostasis. Emerging evidence suggests that ANGPTL1 may also influence cellular signaling pathways related to inflammation and endothelial function, positioning it as a potential therapeutic target for treating conditions such as atherosclerosis and obesity. The recombinant production of ANGPTL1 protein allows for in-depth studies of its structure-function relationships and biological roles, facilitating the exploration of its therapeutic potential. Understanding the mechanisms through which ANGPTL1 exerts its effects can offer novel insights into disease mechanisms and lead to the development of new treatments for related disorders. Thus, the study of ANGPTL1 recombinant protein is essential for unraveling its complex biology and therapeutic applications.
