Cat: PA2000-1373

Recombinant Human MTNR1C Protein,His

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Analytical Data

  • 基因名

    MTNR1C

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    MTNR1C;Melatonin receptor type 1C

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    P49219

  • 表达区间

    1-420aa

  • 氨基酸序列

    MMEVNSTCLDCRTPGTIRTEQDAQDSASQGLTSALAVVLIFTIVVDVLGNILVILSVLRNKKLQNAGNLFVVSLSIADLVVAVYPYPVILIAIFQNGWTLGNIHCQISGFLMGLSVIGSVFNITAIAINRYCYICHSLRYDKLYNQRSTWCYLGLTWILTIIAIVPNFFVGSLQYDPRIFSCTFAQTVSSSYTITVVVVHFIVPLSVVTFCYLRIWVLVIQVKHRVRQDFKQKLTQTDLRNFLTMFVVFVLFAVCWAPLNFIGLAVAINPFHVAPKIPEWLFVLSYFMAYFNSCLNAVIYGVLNQNFRKEYKRILMSLLTPRLLFLDTSRGGTEGLKSKPSPAVTNNNQADMLGEARSLWLSRRNGAKMVIIIRPRKAQIAIIHQIFWPQSSWATCRQDTKITGEEDGCRELCKDGISQR

  • 分子量

    47.4 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

MTNR1C, also known as melatonin receptor 1C, is a member of the G protein-coupled receptor (GPCR) family that plays a crucial role in mediating the physiological effects of melatonin, a hormone primarily produced by the pineal gland. Research into MTNR1C has gained significant attention due to its involvement in various biological processes, including circadian rhythm regulation, reproductive functions, and seasonal reproductive adaptations in animals. The receptor is distinct from its counterparts, MTNR1A and MTNR1B, with unique expression patterns and functional implications in different tissues. Notably, MTNR1C has been implicated in several health conditions, including sleep disorders, mood disorders, and certain cancers, making it a potential target for therapeutic interventions. However, the limited availability of purified and functional MTNR1C proteins has hindered detailed studies of its signaling pathways and structural biology. Recent advancements in recombinant protein technology allow for the expression, purification, and characterization of MTNR1C, offering a valuable tool for elucidating its mechanisms of action and exploring its potential as a drug target. Understanding MTNR1C's function at a molecular level could lead to novel treatments for melatonin-related disorders and deeper insights into circadian biology. As research progresses, the development of MTNR1C recombinant proteins will facilitate the investigation of drug interactions and signaling cascades, enhancing our understanding of this important receptor and its role in health and disease.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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