Analytical Data
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基因名
OR5A2
- Application
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别名
OR5A2; Olfactory receptor 5A2; Olfactory receptor OR11-248
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8NGI9
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表达区间
1-324 aa
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氨基酸序列
MAVGRNNTIVTKFILLGLSDHPQMKIFLFMLFLGLYLLTLAWNLSLIALIKMDSHLHMPM YFFLSNLSFLDICYVSSTAPKMLSDIITEQKTISFVGCATQYFVFCGMGLTECFLLAAMA YDRYAAICNPLLYTVLISHTLCLKMVVGAYVGGFLSSFIETYSVYQHDFCGPYMINHFFC DLPPVLALSCSDTFTSEVVTFIVSVVVGIVSVLVVLISYGYIVAAVVKISSATGRTKAFS TCASHLTAVTLFYGSGFFMYMRPSSSYSLNRDKVVSIFYALVIPVVNPIIYSFRNKEIKN AMRKAMERDPGISHGGPFIFMTLG
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分子量
36.0 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
OR5A2, a member of the olfactory receptor (OR) family, has garnered significant interest in recent years due to its potential role in the olfactory sensory system and its implications in various physiological and pathological processes. Unlike typical receptors, ORs like OR5A2 are primarily located in the nasal epithelium, where they play a crucial role in detecting odorant molecules, thus contributing to our sense of smell. Recent studies have suggested that OR5A2 may also be involved in non-canonical signaling pathways, influencing various cellular responses beyond olfaction, including modulation of immune responses and neuroprotection. The recombinant production of OR5A2 protein is essential for further understanding its structural, functional, and signaling characteristics through biochemical assays and molecular biology techniques. By generating and purifying OR5A2, researchers aim to investigate its ligand binding specificity, downstream signaling mechanisms, and potential therapeutic applications, particularly in diseases linked to olfactory dysfunction or neurodegenerative disorders. These studies not only expand our fundamental understanding of olfactory signaling but may also pave the way for targeted therapies that harness the unique properties of olfactory receptors like OR5A2. Thus, the exploration of recombinant OR5A2 presents a promising avenue for biomedical research, linking basic science to potential clinical applications.
