Analytical Data
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Gene name
SPRR4
- Application
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Alternative Names
SPRR4；Small proline-rich Protein 4
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96PI1
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Expression Region
1-79aa
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AA Sequence
MSSQQQQRQQ QQCPPQRAQQ QQVKQPCQPP PVKCQETCAP KTKDPCAPQV KKQCPPKGTI IPAQQKCPSA QQASKSKQK
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Molecular Weight
8.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SPRR4 (Small Proline-Rich Protein 4) is part of the small proline-rich protein family predominantly expressed in various epithelial tissues. Its research has garnered attention due to its potential roles in skin barrier function, cellular proliferation, and response to stress. User-regulated expression of SPRR4 has been observed in skin keratinocytes, where it may play a crucial role in keratinization and wound healing processes. Furthermore, studies indicate that SPRR4 is involved in the pathophysiology of certain skin disorders, making it a candidate for understanding skin health and disease mechanisms. Investigating SPRR4 as a recombinant protein can facilitate the exploration of its functional properties and interactions at the molecular level, providing insights into its biological significance. The production and characterization of SPRR4 recombinant protein allow researchers to delve into its structure-function relationships, assess its role in cellular pathways, and evaluate its potential as a therapeutic target or biomarker for epidermal health and skin diseases. Additionally, enhanced understanding of SPRR4 might contribute to the development of novel strategies for skin-related therapies, particularly in conditions characterized by abnormal keratinocyte behavior or impaired barrier function. Overall, the study of SPRR4 recombinant protein is pivotal for advancing our knowledge of epithelial biology and its clinical applications in dermatology.
