Analytical Data
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基因名
AMHR2
- Application
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别名
AMH type II receptor; AMHR; AMHR2; AMHR2_HUMAN; Anti Mullerian hormone receptor
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q16671
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表达区间
1-573aa
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氨基酸序列
MLGSLGLWALLPTAVEAPPNRRTCVFFEAPGVRGSTKTLGELLDTGTELPRAIRCLYSRCCFGIWNLTQDRAQVEMQGCRDSDEPGCESLHCDPSPRAHPSPGSTLFTCSCGTDFCNANYSHLPPPGSPGTPGSQGPQAAPGESIWMALVLLGLFLLLLLLLGSIILALLQRKNYRVRGEPVPEPRPDSGRDWSVELQELPELCFSQVIREGGHAVVWAGQLQGKLVAIKAFPPRSVAQFQAERALYELPGLQHDHIVRFITASRGGPGRLLSGPLLVLELHPKGSLCHYLTQYTSDWGSSLRMALSLAQGLAFLHEERWQNGQYKPGIAHRDLSSQNVLIREDGSCAIGDLGLALVLPGLTQPPAWTPTQPQGPAAIMEAGTQRYMAPELLDKTLDLQDWGMALRRADIYSLALLLWEILSRCPDLRPDSSPPPFQLAYEAELGNTPTSDELWALAVQERRRPYIPSTWRCFATDPDGLRELLEDCWDADPEARLTAECVQQRLAALAHPQESHPFPESCPRGCPPLCPEDCTSIPAPTILPCRPQRSACHFSVQQGPCSRNPQPACTLSPV
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分子量
62 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
AMHR2 (Anti-Müllerian Hormone Receptor Type 2) is a critical component in the reproductive system, playing a significant role in sexual differentiation and gonadal function. Its primary function involves binding Anti-Müllerian Hormone (AMH), which is essential for the regression of the Müllerian ducts during male embryonic development. Research has shown that AMHR2 is involved not only in reproductive organ development but also in other biological processes, including cancer progression and tissue remodeling. Alterations in the expression or function of AMHR2 have been associated with reproductive disorders, such as androgen insensitivity syndrome and polycystic ovary syndrome. Additionally, its role in tumor biology, particularly in ovarian cancer, has garnered attention, as AMHR2 may serve as a potential therapeutic target or biomarker. Consequently, the recombinant protein of AMHR2 is studied to elucidate its structure-function relationships, explore its signaling mechanisms, and assess its implications in both normal physiology and pathological conditions. Enhanced understanding of AMHR2 may lead to innovative therapeutic strategies and improved management of related disorders. The exploration of AMHR2 recombinant protein also opens possibilities for the development of AMH-based therapies and diagnostic tools, thus underscoring the importance of ongoing research in this area.
