Analytical Data
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Gene name
ALMS1P
- Application
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Alternative Names
Alstrom syndrome Protein 1
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96L16
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Expression Region
1-210aa
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AA Sequence
MPMKEFPGLFLWKMWSLDKKKENMLKTHDPGISRLEPVTKTKPWREPLWERNWQGQHLDSRGYLAGPGREDGRNPLKLFVRATLQESLQFHRPDFISHIWERIKRLKLIVQERKLQSMLKSERDALFDIDRERQGHQNRMRPLPKRVFLAVQKNKPISKKEMIQRSKRTHAGGTVAQRLPGALWVKERLPGKGEKHPGIPVTSGSSTQTM
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Molecular Weight
49.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ALMS1P, a paralog of the ALMS1 gene, has recently garnered attention in the field of molecular biology due to its potential implications in the study of genetic disorders and cellular functions. The ALMS1 gene is known to be linked to Alström syndrome, a rare genetic disorder characterized by obesity, diabetes, congestive heart failure, and progressive vision and hearing loss. Given the importance of ALMS1 in cell signaling, ciliary function, and the regulation of metabolic pathways, researchers are exploring ALMS1P to unravel its biological roles and contribute to a better understanding of its expression, regulation, and potential involvement in disease mechanisms. Preliminary studies suggest that ALMS1P may retain some functional properties of its counterpart while exhibiting distinct regulatory features, making it a promising candidate for investigating gene evolution and redundancy. Additionally, the recombinant protein derived from ALMS1P can be utilized in biochemical assays and structural studies, aiding in the elucidation of its interactions with other cellular components. Overall, research on ALMS1P represents a significant step towards comprehending the complexities of the ALMS1 gene family and their relevance in human health and disease.
