Analytical Data
-
Gene name
SRFBP1
- Application
-
Alternative Names
SRFBP1；GLUT4；Solute carrier family 2. facilitated glucose transporter member 4
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q8NEF9
-
Expression Region
2-429aa
-
AA Sequence
AQPGTLNLN NEVVKMRKEV KRIRVLVIRK LVRSVGRLKS KKGTEDALLK NQRRAQRLLE EIHAMKELKP DIVTKSALGD DINFEKIFKK PDSTATERAI ARLAVHPLLK KKIDVLKAAV QAFKEARQNV AEVESSKNAS EDNHSENTLY SNDNGSNLQR EATVISEQKV KETKILAKKP IHNSKEKIAK MEHGPKAVTI ANSPSKPSEK DSVVSLESQK TPADPKLKTL SQTKKNKGSD SSLSGNSDGG EEFCEEEKEY FDDSTEERFY KQSSMSEDSD SGDDFFIGKV RRTRKKESSC HSSVKEQKPL EKVFLKEDTG ETHGDTRNDK IKPSTETRKL ESVFFHSLSG SKSSRRNFKE QAPKTRSLDF PQNEPQIKNQ FNKKLSGRLE NTKQQLQLPL HPSWEASRRR KEQQSNIAVF QGKKITFDD
-
Molecular Weight
48.6 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SRFBP1 (SRF-selective binding protein 1) is a key regulatory protein that plays a significant role in gene expression and cellular signaling pathways. It interacts with serum response factor (SRF), a transcription factor that is crucial for the regulation of genes involved in muscle development, growth, and response to various environmental stimuli. The study of SRFBP1 and its recombinant forms has garnered interest due to its potential implications in understanding various physiological and pathological conditions, including muscle-related diseases, cardiovascular disorders, and cancer progression. Research has shown that SRFBP1 can modulate SRF activity by influencing its binding to DNA and altering the expression of downstream target genes. The generation of recombinant SRFBP1 protein allows researchers to investigate its biochemical properties, protein-protein interactions, and functional roles within the cell. Additionally, recombinant proteins can be used in vivo and in vitro studies to elucidate the mechanisms by which SRFBP1 regulates gene expression and contributes to cellular processes. This research has the potential to uncover novel therapeutic targets and strategies for diseases where SRF and its regulatory networks are disrupted. As a result, the recombinant production of SRFBP1 continues to be an important focus within molecular biology and biomedical research, paving the way for advancements in our understanding of gene regulation and its implications in health and disease.
