Analytical Data
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基因名
SNX5
- Application
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别名
SNX5;Sorting nexin-5
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y5X3
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表达区间
1-404aa
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氨基酸序列
MASMTGGQQMGRGEFMAAVPELLQQQEEDRSKLRSVSVDLNVDPSLQIDI PDALSERDKVKFTVHTKTTLPTFQSPEFSVTRQHEDFVWLHDTLIETTDY AGLIIPPAPTKPDFDGPREKMQKLGEGEGSMTKEEFAKMKQELEAEYLAV FKKTVSSHEVFLQRLSSHPVLSKDRNFHVFLEYDQDLSVRRKNTKEMFGG FFKSVVKSADEVLFTGVKEVDDFFEQEKNFLINYYNRIKDSCVKADKMTR SHKNVADDYIHTAACLHSLALEEPTVIKKYLLKVAELFEKLRKVEGRVSS DEDLKLTELLRYYMLNIEAAKDLLYRRTKALIDYENSNKALDKARLKSKD VKLAEAHQQECCQKFEQLSESAKEELINFKRKRVAAFRKNLIEMSELEIK HARNNVSLLQSCIDLFKNN
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分子量
48 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SNX5 (Sorting Nexin 5) is a member of the sorting nexin family, which plays a crucial role in intracellular trafficking and membrane dynamics. Research has shown that SNX5 is involved in various cellular processes, including endocytosis, autophagy, and the sorting of membrane proteins. Its function is particularly significant in the context of immune responses and cellular signaling pathways. Abnormalities in SNX5 expression or function have been implicated in several diseases, including cancer and neurodegenerative disorders. Given its pivotal role in cellular processes, studying recombinant SNX5 proteins has become essential for understanding the mechanisms underlying its function and regulation. Researchers aim to express and purify SNX5 proteins to investigate their structural properties and interactions with other cellular components. This research is critical for elucidating its biological roles and discovering potential therapeutic targets, as manipulating SNX5 activity could pave the way for novel treatments in conditions where its functionality is disrupted. Through advanced techniques such as crystallography and biophysical assays, insights gained from these studies will contribute significantly to the broader knowledge of membrane trafficking and its implications in health and disease.
