Analytical Data
-
Gene name
RRAS
- Application
-
Alternative Names
RRAS;Ras-related Protein R-Ras
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
P10301
-
Expression Region
1-215aa
-
AA Sequence
MSSGAASGTG RGRPRGGGPG PGDPPPSETH KLVVVGGGGV GKSALTIQFI QSYFVSDYDP TIEDSYTKIC SVDGIPARLD ILDTAGQEEF GAMREQYMRA GHGFLLVFAI NDRQSFNEVG KLFTQILRVK DRDDFPVVLV GNKADLESQR QVPRSEASAF GASHHVAYFE ASAKLRLNVD EAFEQLVRAV RKYQEQELPP SPPSAPRKKG GGCPC
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The research on RRAS (Regulator of Ras) recombinant protein has gained significant attention due to its crucial role in cellular signaling pathways and cancer biology. RRAS is a member of the Ras superfamily of small GTPases, which are pivotal regulators of various cellular functions such as growth, differentiation, and survival. Mutations in RRAS have been implicated in several malignancies, highlighting its potential as a therapeutic target. Moreover, the ability of RRAS to interact with multiple downstream effectors affects pathways like the MAPK and PI3K/Akt signaling cascades, which are integral to tumor development and progression. The production of RRAS recombinant protein allows for detailed studies of its biochemical properties and interactions, facilitating the exploration of its role in oncogenesis. Understanding RRAS function at a molecular level can provide insights into novel cancer treatment strategies, making it a promising candidate for drug development. Furthermore, the optimization of protocols for the expression and purification of RRAS may contribute to the advancement of therapeutic interventions aimed at modulating its activity in disease contexts. Overall, research into RRAS recombinant protein serves as a vital interdisciplinary effort bridging molecular biology, cancer research, and therapeutic innovation.
