Analytical Data
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Gene name
RASL12
- Application
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Alternative Names
RASL12;RIS;Ras-like Protein family member 12
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9NYN1
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Expression Region
1-266aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMSSVFGK PRAGSGPQSA PLEVNLAILG RRGAGKSALT VKFLTKRFIS EYDPNLEDTY SSEETVDHQP VHLRVMDTAD LDTPRNCERY LNWAHAFLVV YSVDSRQSFD SSSSYLELLA LHAKETQRSI PALLLGNKLD MAQYRQVTKA EGVALAGRFG CLFFEVSACL DFEHVQHVFH EAVREARREL EKSPLTRPLF ISEERALPHQ APLTARHGLA SCTFNTLSTI NLKEMPTVAQ AKLVTVKSSR AQSKRKAPTL TLLKGFKIF
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Molecular Weight
32 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RASL12 is a member of the Ras protein family, known for its role in cellular signaling pathways that regulate growth, differentiation, and apoptosis. The study of RASL12 has garnered attention due to its unique structural and functional characteristics compared to other Ras homologs. Unlike traditional Ras proteins, which are primarily involved in oncogenic pathways, RASL12 appears to have distinct regulatory effects that may influence tumor suppression and cellular homeostasis. Researchers have begun to explore the implications of RASL12's role in cancer biology, particularly its potential involvement in modulating signaling cascades that govern cell proliferation and survival. Investigating the functional dynamics of RASL12, including the molecular mechanisms by which it interacts with various signaling partners, could provide insights into its contribution to tumorigenesis. Additionally, the potential for RASL12 as a therapeutic target in cancer treatment is an area of growing interest, as understanding its reconstitution and activation could lead to novel interventions. Overall, the exploration of RASL12 as a recombinant protein offers a promising frontier in the understanding of Ras-related signaling networks and their impacts on cancer biology.
