Analytical Data
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基因名
RASD2
- Application
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别名
RASD2;TEM2;GTP-binding Protein Rhes
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q96D21
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表达区间
1-266aa
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氨基酸序列
MGSSHHHHHHSSGLVPRGSHMGSMMKTLSSGNCTLSVPAKNSYRMVVLGA SRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGN HPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKT KEAAELPMVICGNKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNT NVDEMFYVLFSMAKLPHEMSPALHRKISVQYGDAFHPRPFCMRRVKEMDA YGMVSPFARRPSVNSDLKYIKAKVLREGQARERDKCTIQ
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分子量
33 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RASD2, a member of the RAS family of small GTPases, has garnered significant attention in recent years due to its potential roles in cellular signaling and cancer biology. Unlike its well-known homologs, RASD2 predominantly functions as a GDP-bound form, acting as a negative regulator of various signaling pathways. This unique feature positions RASD2 as a critical player in modulating cellular responses to stimuli and maintaining homeostasis. Research has suggested that RASD2 is involved in processes such as neuronal differentiation, cell proliferation, and apoptosis. Moreover, its altered expression has been linked to several malignancies, indicating its potential as a biomarker and therapeutic target in cancer treatment. Understanding the structural and functional dynamics of RASD2, especially through the study of its recombinant protein, can provide insights into its regulatory mechanisms and interactions with other cellular partners. Investigating the properties of RASD2 reconstituted in vitro allows for detailed analysis of its biochemical behavior and impacts on signaling cascades. Thus, the study of RASD2 recombinant protein holds promise not only for enhancing our understanding of fundamental biological processes but also for developing novel strategies in cancer therapy and other diseases where RASD2 may play a pivotal role.
