Analytical Data
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Gene name
RAB14
- Application
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Alternative Names
RAB14;Ras-related Protein Rab-14
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P61106
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Expression Region
2-215aa
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AA Sequence
ATAPYNYSY IFKYIIIGDM GVGKSCLLHQ FTEKKFMADC PHTIGVEFGT RIIEVSGQKI KLQIWDTAGQ ERFRAVTRSY YRGAAGALMV YDITRRSTYN HLSSWLTDAR NLTNPNTVII LIGNKADLEA QRDVTYEEAK QFAEENGLLF LEASAKTGEN VEDAFLEAAK KIYQNIQDGS LDLNAAESGV QHKPSAPQGG RLTSEPQPQR EGCGC
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RAB14 is a member of the RAB GTPase family, known for its role in intracellular trafficking and vesicle transport. As a small GTP-binding protein, RAB14 is implicated in various cellular processes, including endocytosis, exocytosis, and lysosomal function. Recent studies have highlighted its significance in regulating the transport and localization of specific proteins and organelles within cells. Disruptions in RAB14 function have been linked to various pathological conditions, including cancer and neurodegenerative diseases, making it a potential target for therapeutic strategies. The recombination and study of RAB14 protein provide valuable insights into its mechanisms of action and interactions with other cellular components. By generating recombinant RAB14, researchers can effectively analyze its GTPase activity, binding partners, and role in cellular signaling pathways. Such investigations are crucial for understanding the underlying molecular mechanisms of RAB14 and its contributions to health and disease. Furthermore, studying RAB14 in different biological systems can shed light on its evolutionary conservation and potential as a biomarker or therapeutic target in diverse medical contexts. This underscores the importance of RAB14 in both basic and applied biomedical research, aiming to elucidate its functions and potential impact on human health.
