Analytical Data
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基因名
MRPL51
- Application
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别名
39S ribosomal protein L51; 39S ribosomal protein L51 mitochondrial; bMRP-64; bMRP64; CDA09; HSPC241; L51mt; mitochondrial; mitochondrial ribosomal protein 64; mitochondrial ribosomal protein bMRP64; mitochondrial ribosomal protein L51 ; MRP-L51; MRP64; mrpl51; RM51_HUMAN
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q4U2R6
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表达区间
32-128 aa
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氨基酸序列
IGIRLTLPP PKVVDRWNEK RAMFGVYDNI GILGNFEKHP KELIRGPIWL RGWKGNELQR CIRKRKMVGS RMFADDLHNL NKRIRYLYKH FNRHGKFR
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分子量
15.0 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MRPL51, or mitochondrial ribosomal protein L51, is a crucial component of the mitochondrial ribosome, playing a vital role in the protein synthesis within mitochondria. Its study has gained prominence due to its involvement in mitochondrial biogenesis and function, which are essential for cellular energy metabolism. Mitochondrial dysfunction is linked to various diseases, including neurodegenerative disorders and metabolic syndromes, making MRPL51 a potential target for therapeutic strategies. Recent research has indicated that alterations in MRPL51 expression can affect mitochondrial translation efficiency and impact cellular stress responses. Understanding the structure and function of MRPL51 is critical for elucidating the mechanisms underlying mitochondrial-related diseases. Furthermore, its role in mitochondrial diseases highlights the importance of studying this protein to develop targeted interventions. Investigations into MRPL51 have the potential to uncover new insights into mitochondrial dynamics and therapeutic options for conditions arising from mitochondrial deficiencies. As such, MRPL51 is not only a key player in mitochondrial function but also a focal point for advancements in biomedical research aimed at understanding and treating mitochondrial disorders.
