Analytical Data
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基因名
MPP7
- Application
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别名
FLJ32798; MAGUK p55 subfamily member 7; Membrane protein palmitoylated 7 MAGUK p55 subfamily member 7; MPP7; MPP7_HUMAN; Palmitoylated membrane protein 7
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q5T2T1
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表达区间
1-576 aa
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氨基酸序列
MPALSTGSGS DTGLYELLAA LPAQLQPHVD SQEDLTFLWD MFGEKSLHSL VKIHEKLHYY EKQSPVPILH GAAALADDLA EELQNKPLNS EIRELLKLLS KPNVKALLSV HDTVAQKNYD PVLPPMPEDI DDEEDSVKII RLVKNREPLG ATIKKDEQTG AIIVARIMRG GAADRSGLIH VGDELREVNG IPVEDKRPEE IIQILAQSQG AITFKIIPGS KEETPSKEGK MFIKALFDYN PNEDKAIPCK EAGLSFKKGD ILQIMSQDDA TWWQAKHEAD ANPRAGLIPS KHFQERRLAL RRPEILVQPL KVSNRKSSGF RKSFRLSRKD KKTNKSMYEC KKSDQYDTAD VPTYEEVTPY RRQTNEKYRL VVLVGPVGVG LNELKRKLLI SDTQHYGVTV PHTTRARRSQ ESDGVEYIFI SKHLFETDVQ NNKFIEYGEY KNNYYGTSID SVRSVLAKNK VCLLDVQPHT VKHLRTLEFK PYVIFIKPPS IERLRETRKN AKIISSRDDQ GAAKPFTEED FQEMIKSAQI MESQYGHLFD KIIINDDLTV AFNELKTTFD KLETETHWVP VSWLHS
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分子量
65.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MPP7, a member of the MAGUK (membrane-associated guanylate kinase) family, plays a crucial role in the organization of cell junctions and the regulation of signaling pathways in various tissues. It is predominantly expressed in the brain and has been implicated in synaptic function and neurodevelopmental processes. Recent studies have highlighted the importance of MPP7 in maintaining the integrity of tight junctions in epithelial cells, which are essential for barrier function and cell polarization. Dysregulation of MPP7 expression or its interactions with other proteins has been linked to several diseases, including cancer and neurological disorders. Research on MPP7 recombinant proteins seeks to elucidate its structure-function relationship and molecular mechanisms, providing insights into its role in cellular communication and potential as a therapeutic target. By generating MPP7 recombinant proteins, scientists can investigate its biochemical properties, interaction with other signaling molecules, and potential modifications that may affect its function. Understanding MPP7's precise mechanisms could pave the way for novel strategies in treating diseases associated with its dysfunction, thus underscoring the relevance of MPP7 research in both basic biological science and clinical applications.
