Analytical Data
-
基因名
Atf5
- Application
-
别名
Atf5；ATFX；Cyclic AMP-dependent transcription factor ATF-5
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
O70191
-
表达区间
1-283aa
-
氨基酸序列
MSLLATLGLELDRALLPASGLGWLVDYGKLPLAPAPLGPYEVLGGALEGGLPGGGEPLAGDGFSDWMTERVDFTALLPLEAPLPPGTLPPPSPAPPDLEAMASLLKKELEQMEDFFLDAPLLPPPSPPPPPPPAAAPSLPLPLPLPTFDLPQPPTLDTLDLLAVYCRSEAGPGDSGLSTLPVPQQPPPLAPLPSPARPAPYPSPASTRGDRKQKKRDQNKSAALRYRQRKRAEGEALEGECQGLEARNRELRERAESVEREIQYVKDLLIEVYKARSQRTRST
-
分子量
37.8 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ATF5 (Activating Transcription Factor 5) is a member of the basic leucine zipper (bZIP) family of transcription factors that plays a pivotal role in cellular stress responses, particularly in the context of the endoplasmic reticulum (ER) stress response and neuroprotection. Research on ATF5 has gained momentum due to its significance in various physiological and pathological processes, including cell survival, differentiation, and apoptosis. It has been implicated in several diseases such as neurodegenerative disorders, cancers, and metabolic syndromes. The ability of ATF5 to modulate gene expression in response to stress makes it an important protein for understanding cellular homeostasis and adaptation. Recombinant ATF5 proteins are often generated for functional studies to elucidate its mechanisms of action and regulatory pathways. These recombinant proteins facilitate the investigation of ATF5's role in gene regulation, protein interactions, and its contribution to the adaptive stress response. Moreover, studying ATF5 provides insights into potential therapeutic targets for conditions where its function is altered, highlighting the need for detailed characterization of this transcription factor and exploring its utility in biomedical research.
