Analytical Data
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Gene name
PPP3R2
- Application
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Alternative Names
PPP3R2;CBLP;PPP3RL;Calcineurin subunit B type 2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96LZ3
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Expression Region
1-173aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MSTMGNEASY PAEMCSHFDN DEIKRLGRRF KKLDLDKSGS LSVEEFMSLP ELRHNPLVRR VIDVFDTDGD GEVDFKEFIL GTSQFSVKGD EEQKLRFAFS IYDMDKDGYI SNGELFQVLK MMVGNNLTDW QLQQLVDKTI IILDKDGDGK ISFEEFSAVV RDLEIHKKLV LIV
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Molecular Weight
22 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PPP3R2, also known as Protein Phosphatase 3 Regulatory Subunit B'gamma, belongs to the family of regulatory subunits that modulate the activity of protein phosphatase 3 (PP3), a critical enzyme involved in various cellular processes, including cell division, growth, and apoptosis. Research into PPP3R2 has gained significance due to its potential role in regulating signal transduction pathways, particularly those involving calcium and calmodulin. Alterations in PPP3R2 expression have been implicated in various diseases, including cancers and neurodegenerative disorders. Studies have shown that overexpression or dysregulation of PPP3R2 can disrupt normal cellular functions, highlighting its importance in maintaining cellular homeostasis. Furthermore, the ability of PPP3R2 to interact with different protein partners enhances its functional diversity, making it a critical focus for understanding disease mechanisms. Recent advances in structural biology and biochemistry have facilitated the generation of recombinant PPP3R2 protein, enabling researchers to explore its biochemical properties and interactions in detail. This research not only provides insights into the fundamental roles of PPP3R2 in cellular signaling but also opens avenues for developing targeted therapies that could modulate its activity in pathological conditions. As such, PPP3R2 stands as a promising candidate for further investigation in the context of drug development and personalized medicine.











