Analytical Data
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基因名
MKI67IP
- Application
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别名
hNIFK; MK67I_HUMAN; MKI67 FHA Domain Interacting Nucleolar Phosphoprotein; MKI67 FHA domain-interacting nucleolar phosphoprotein; mki67ip; NOPP34; Nucleolar phosphoprotein Nopp34; Nucleolar protein interacting with the FHA domain of pKI 67; Nucleolar protein interacting with the FHA domain of pKI-67; pKi67
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BYG3
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表达区间
2-293 aa
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氨基酸序列
ATFSGPAGP ILSLNPQEDV EFQKEVAQVR KRITQRKKQE QLTPGVVYVR HLPNLLDETQ IFSYFSQFGT VTRFRLSRSK RTGNSKGYAF VEFESEDVAK IVAETMNNYL FGERLLECHF MPPEKVHKEL FKDWNIPFKQ PSYPSVKRYN RNRTLTQKLR MEERFKKKER LLRKKLAKKG IDYDFPSLIL QKTESISKTN RQTSTKGQVL RKKKKKVSGT LDTPEKTVDS QGPTPVCTPT FLERRKSQVA ELNDDDKDDE IVFKQPISCV KEEIQETQTP THSRKKRRRS SNQ
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分子量
34.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The MKI67IP (MKI67 Interacting Protein) is a crucial protein involved in the regulation of cell proliferation and the cell cycle. It has garnered significant research interest due to its role in cancer biology, particularly in the context of tumor growth and progression. MKI67IP is known to interact with the Ki-67 protein, a well-established marker of cellular proliferation, thereby influencing the processes of mitosis and chromatin dynamics. Studies have suggested that MKI67IP may contribute to the maintenance of cell division and could be a potential target for therapeutic interventions in various cancers. Furthermore, understanding the molecular mechanisms underlying its function may provide insights into the dysregulation of cell proliferation in cancerous tissues. As researchers delve deeper into the role of MKI67IP, its potential implications in diagnostics and treatment strategies continue to be a focal point, highlighting the importance of this protein in oncology research. Given the increasing incidence of cancer worldwide, the investigation of MKI67IP and its related pathways is not only timely but also critical for developing novel approaches to improve patient outcomes.
