Analytical Data
-
Gene name
SNCaIP1
- Application
-
Alternative Names
SNCaIP1；
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
A0A6A4XDD4
-
Expression Region
1-336aa
-
AA Sequence
MEPTLIRNLSDHHGNNLAHVLAACGHVQALAWLVGTCGHVLSEALADENKHGLTPSVAAVRCGKLDVIQWMVENTVIRERLFTREGERSLLHAAAKYGQVEITSWCADQLLREGQGMDLADHHGDTPLHLAAKTGNTAVAQKLLERNASVTARNDMSLKPFELAVHHGHSACAEYLLTYEALGDLAVDFTSLEAEAGRLQHENADYKNNFREVLSVSRKLLREREDMCKDLSRLHESTLELHDRLLGQLQQLSAENRQLRRRLQEPADEPADQLDESAELANTLHVRWQHCQRAWFSAPLADTQHRLLMAEQAWKRLRASRKDNVSSMTSAQEIVR
-
Molecular Weight
37.7 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SNCaIP1, or Synaptosomal-associated protein of 1, is a crucial protein involved in synaptic function and neurotransmitter release, playing a significant role in the nervous system's dynamics. Its importance has been underscored in various studies linking abnormal SNCaIP1 expression to neurodegenerative diseases and synaptic disorders. The research surrounding SNCaIP1 recombinant protein focuses on its structural and functional characteristics, aiming to elucidate its role in synaptic transmission and signaling pathways within neurons. By producing recombinant SNCaIP1, researchers can investigate its biochemical properties, interactions with other proteins, and influence on synaptic plasticity in controlled environments. This understanding is particularly relevant for developing therapeutic strategies targeting SNCaIP1-related malfunctions that contribute to conditions such as Alzheimer's disease and autism spectrum disorders. Furthermore, recombinant SNCaIP1 can serve as a vital tool for high-throughput screening of potential drugs and compounds that modulate synaptic activity, offering insights into the intricate mechanisms governing neuronal communication. As research progresses, the characterization and application of SNCaIP1 recombinant protein may pave the way for novel interventions in synaptic and neurodegenerative disorders, emphasizing the convergence of basic science and therapeutic innovation.
