Analytical Data
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Gene name
MGC10540
- Application
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Alternative Names
Dermal papilla derived protein 9; Dermal papilla-derived protein 9; DERP9; EAP20; ELL associated protein of 20 kDa; ELL-associated protein of 20 kDa; ESCRT-II complex subunit VPS25; FAP20; HGNC:28122; hVps25; MGC10540; Vacuolar protein sorting 25 homolog (S. cerevisiae); Vacuolar protein sorting associated protein 25; Vacuolar protein-sorting-associated protein 25; VPS25; VPS25_HUMAN
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9BRG1
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Expression Region
1-176 aa
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AA Sequence
MAMSFEWPWQ YRFPPFFTLQ PNVDTRQKQL AAWCSLVLSF CRLHKQSSMT VMEAQESPLF NNVKLQRKLP VESIQIVLEE LRKKGNLEWL DKSKSSFLIM WRRPEEWGKL IYQWVSRSGQ NNSVFTLYEL TNGEDTEDEE FHGLDEATLL RALQALQQEH KAEIITVSDG RGVKFF
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Molecular Weight
20.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MGC10540, also known as the human gene ECHS1, encodes a mitochondrial enzyme that plays a critical role in the metabolism of acyl-CoA derivatives and participates in the beta-oxidation of fatty acids. Research into MGC10540 has gained attention due to its potential implications in various metabolic disorders and mitochondrial diseases. The protein's function in energy production and fatty acid metabolism is essential, as impairments in these pathways can lead to significant health issues, including obesity, diabetes, and cardiovascular diseases. Furthermore, MGC10540 has been identified as a candidate gene for certain hereditary conditions, making it a focal point in genetic studies. Understanding the structure and function of MGC10540 facilitates the investigation of its role in cellular metabolism and energy homeostasis, thereby providing insights into therapeutic interventions for related diseases. Recent studies employing recombinant protein techniques aim to elucidate the biochemical properties of MGC10540, assess its activity, and explore its interactions with other metabolic pathways. This research not only enhances our comprehension of MGC10540's role in human health but also paves the way for potential applications in drug development and nutritional strategies aimed at optimizing metabolic health.
