Analytical Data
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基因名
comC
- Application
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别名
comC；C11orf83；Ubiquinol-cytochrome-c reductase complex assembly factor 3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O33666
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表达区间
25-40aa
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氨基酸序列
EMRKPDGALFNLFRRR
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分子量
17.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The study of the comC recombinant protein is rooted in its pivotal role in bacterial communication and competence, particularly in the context of genetic transformation in streptococci. ComC is a part of the competence-stimulating peptide (CSP) system, which facilitates the uptake of foreign DNA by bacteria, a process crucial for horizontal gene transfer and adaptation in various environments. Research on comC has expanded due to its potential applications in biotechnology, including antibiotic resistance studies and the development of novel vaccine strategies. Understanding the structure and function of comC can offer insights into the molecular mechanisms of competence and the regulatory pathways involved. Furthermore, with the rise of antibiotic-resistant strains of bacteria, investigating comC may reveal new targets for therapeutic interventions to enhance bacterial transformation and potentially combat resistance. Given its significance in microbial ecology and genetics, the exploration of comC recombinant protein not only enriches our understanding of fundamental microbial processes but also opens avenues for innovative approaches in medicine and genetic engineering.
