Analytical Data
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基因名
SSRa
- Application
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别名
SSRa；TRAPA；Translocon-associated Protein subunit alpha
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P43307
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表达区间
1-286aa
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氨基酸序列
MRLLPRLLLLLLLVFPATVLFRGGPRGLLAVAQDLTEDEETVEDSIIEDEDDEAEVEEDEPTDLVEDKEEEDVSGEPEASPSADTTILFVKGEDFPANNIVKFLVGFTNKGTEDFIVESLDASFRYPQDYQFYIQNFTALPLNTVVPPQRQATFEYSFIPAEPMGGRPFGLVINLNYKDLNGNVFQDAVFNQTVTVIEREDGLDGETIFMYMFLAGLGLLVIVGLHQLLESRKRKRPIQKVEMGTSSQNDVDMSWIPQETLNQINKASPRRLPRKRAQKRSVGSDE
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分子量
32.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SSRa (Small SpoU-like protein A) is a crucial protein implicated in various biological processes, including RNA modification and regulation. Originally identified as a member of the SpoU family of methyltransferases, SSRa is known for its role in catalyzing the 2'-O-methylation of ribosomal RNA, which is vital for ribosome biogenesis and function. The study of SSRa and its recombinant forms is essential for understanding the molecular mechanisms underpinning RNA modifications and their broader implications in cellular physiology and disease. Given the increasing recognition of the importance of RNA methylation in gene expression regulation and its links to cancer and other diseases, producing recombinant SSRa has become a significant area of research. This enables scientists to investigate its enzymatic activities, structural properties, and interactions with other biomolecules. Moreover, the recombinant protein serves as a valuable tool for developing inhibitors or modulators that could potentially lead to therapeutic applications. Understanding the nuances of SSRa function at a molecular level can provide insights into its role in cellular dynamics and highlight its potential as a target for bioengineering and drug development. As research advances, the implications of SSRa in health and disease continue to present exciting opportunities for exploration in both basic and applied sciences.
