Analytical Data
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Gene name
ELMO2
- Application
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Alternative Names
ELMO2；CED12A；KIAA1834；Engulfment and cell motility Protein 2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96JJ3
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Expression Region
1-632aa
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AA Sequence
MERTQSSNMETRLDAMKELAKLSADVTFATEFINMDGIIVLTRLVESGTK LLSHYSEMLAFTLTAFLELMDHGIVSWDMVSITFIKQIAGYVSQPMVDVS ILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVSNQEIQTYAIAL INALFLKAPEDKRQDMANAFAQKHLRSIILNHVIRGNRPIKTEMAHQLYV LQVLTFNLLEERMMTKMDPNDQAQRDIIFELRRIAFDAESDPSNAPGSGT EKRKAMYTKDYKMLGFTNHINPAMDFTQTPPGMLALDNMLYLAKVHQDTY IRIVLENSSREDKHECPFGRSAIELTKMLCEILQVGELPNEGRNDYHPMF FTHDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSK PNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREKIQPEIL ELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNHKVLHYGDLDDNP QGEVTFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSIL YDPDETLNFIAPNKYEYCIWIDGLSALLGKDMSSELTKSDLDTLLSMEMK LRLLDLENIQIPEAPPPIPKEPSSYDFVYHYG
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Molecular Weight
95 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ELMO2 (Engulfment and cell motility 2) is a protein that plays a crucial role in various cellular processes, including cell migration, phagocytosis, and the regulation of the cytoskeleton. Understanding ELMO2's function and the mechanisms underlying its activity is essential for elucidating its contributions to both normal physiological processes and pathological conditions such as cancer metastasis and neurodegenerative diseases. Recent studies have highlighted the importance of ELMO2 in the context of immune response and tissue repair, suggesting that it may serve as a potential therapeutic target. The research on ELMO2 recombinant protein focuses on its expression, characterization, and functional assays to elucidate its role in cellular signaling pathways. This research is vital for developing strategies to manipulate ELMO2 activity, which could open new avenues for treatment in diseases where cell motility and apoptosis are disrupted. As the understanding of ELMO2 expands, it may provide insights into novel molecular mechanisms that underpin various biological functions and disease states, underscoring the significance of continued exploration in this area.
