Analytical Data
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基因名
NUDT4
- Application
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别名
NUDT4;DIPP2;KIAA0487;Diphosphoinositol polyphosphate phosphohydrolase 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NZJ9
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表达区间
1-180aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSMMKFKPN QTRTYDREGF KKRAACLCFR SEQEDEVLLV SSSRYPDQWI VPGGGMEPEE EPGGAAVREV YEEAGVKGKL GRLLGIFENQ DRKHRTYVYV LTVTEILEDW EDSVNIGRKR EWFKVEDAIK VLQCHKPVHA EYLEKLKLGC SPANGNSTVP SLPDNNALFV TAAQTSGLPS SVR
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分子量
23 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
NUDT4, also known as Nudix hydrolase 4, is a member of the Nudix hydrolase family, which plays a crucial role in nucleotide metabolism by catalyzing the hydrolysis of various nucleoside diphosphates and related compounds. Research on NUDT4 has gained attention due to its potential involvement in cellular stress responses, regulation of nucleotide pools, and implications in various diseases, including cancer and metabolic disorders. Understanding the enzymatic activity of NUDT4 is critical for elucidating its functions in cellular processes and its potential role as a therapeutic target. Recent studies have focused on characterizing the kinetic properties of NUDT4, exploring its substrate specificity, and investigating its regulatory mechanisms. Advances in structural biology techniques, such as X-ray crystallography and cryo-electron microscopy, have provided insights into the three-dimensional structure of NUDT4, revealing how substrate binding and catalytic activity are facilitated. The ongoing research aims to further unravel the biological significance of NUDT4, particularly in relation to cellular homeostasis and signal transduction pathways. As scientists continue to explore the NUDT4 enzyme, its potential applications in biotechnology and medicine are also being explored, which could lead to novel strategies for treating diseases associated with dysregulated nucleotide metabolism.












