Analytical Data
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Gene name
TRAF2
- Application
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Alternative Names
TRAF2；TRAP3；TNF receptor-associated factor 2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q12933
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Expression Region
1-501aa
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AA Sequence
MAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCG HRYCSFCLASILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREV ESLPAVCPSDGCTWKGTLKEYESCHEGRCPLMLTECPACKGLVRLGEKER HLEHECPERSLSCRHCRAPCCGADVKAHHEVCPKFPLTCDGCGKKKIPRE KFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWLREHLAMLLSS VLEAKPLLGDQSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTA EACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTY DGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDG TGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQNNREHVIDAFRPD VTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTG L
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Molecular Weight
89 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TRAF2 (TNF Receptor-Associated Factor 2) is a crucial adaptor protein that plays a vital role in the signal transduction pathways of various cytokine receptors, particularly those involved in immune responses, such as the tumor necrosis factor (TNF) receptor family. Research into TRAF2 is driven by its involvement in multiple cellular processes, including apoptosis, inflammation, and cell survival. Dysregulation of TRAF2 signaling has been implicated in numerous pathological conditions, such as autoimmune diseases, cancer, and chronic inflammatory disorders. The recombinant expression of TRAF2 has gained attention as a promising strategy for understanding its functional mechanisms and interacting partners. Characterizing TRAF2 through recombinant protein studies enables researchers to dissect its role in signaling pathways and to elucidate its contribution to disease. Furthermore, TRAF2's potential as a therapeutic target is being explored, making the development of TRAF2 recombinant proteins essential for screening compounds that may modulate its activity. Overall, the ongoing research on TRAF2 recombinant proteins holds significant promise for advancing our knowledge of immune regulation and developing innovative treatments for related diseases.
