Analytical Data
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Gene name
LRRC48
- Application
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Alternative Names
CFAP134; DRC3; Dynein regulatory complex subunit 3; Leucine rich repeat containing 48; Leucine-rich repeat-containing protein 48; LRC48_HUMAN; LRRC48; RP23 135F6.3
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9H069
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Expression Region
1-523aa
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AA Sequence
MNQPCNSMEP RVMDDDMLKL AVGDQGPQEE AGQLAKQEGI LFKDVLSLQL DFRNILRIDN LWQFENLRKL QLDNNIIEKI EGLENLAHLV WLDLSFNNIE TIEGLDTLVN LEDLSLFNNR ISKIDSLDAL VKLQVLSLGN NRIDNMMNII YLRRFKCLRT LSLSRNPISE AEDYKMFICA YLPDLMYLDY RRIDDHTKKL AEAKHQYSID ELKHQENLMQ AQLEDEQAQR EELEKHKTAF VEHLNGSFLF DSMYAEDSEG NNLSYLPGVG ELLETYKDKF VIICVNIFEY GLKQQEKRKT ELDTFSECVR EAIQENQEQG KRKIAKFEEK HLSSLSAIRE ELELPNIEKM ILECSADISE LFDALMTLEM QLVEQLEETI NMFERNIVDM VGLFIENVQS LMAQCRDLEN HHHEKLLEIS ISTLEKIVEG DLDEDLPNDL RALFVDKDTI VNAVGASHDI HLLKIDNRED ELVTRINSWC TRLIDRIHKD EIMRNRKRVK EINQYIDHMQ SELDNLECGD ILD
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Molecular Weight
61.0 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
LRRC48 (Leucine-Rich Repeat Containing 48) has emerged as a focal point of research due to its potential implications in various biological processes, including immune response and cellular signaling. As a member of the leucine-rich repeat (LRR) protein family, LRRC48 is characterized by its repetitive motifs that facilitate protein-protein interactions, suggesting a role in cellular communication and structural organization. Initial studies have indicated that LRRC48 may be involved in the regulation of immune cells, particularly in the context of inflammation and adaptive immunity. Furthermore, its expression patterns and potential involvement in disease mechanisms, such as cancer and autoimmune disorders, have garnered attention. Understanding the functional relevance of LRRC48 through recombinant protein studies can provide insights into its molecular mechanisms and interactions, offering a platform for therapeutic exploration. As researchers focus on characterizing its biochemical properties, including binding affinities and structural characteristics, the potential for LRRC48 as a biomarker or therapeutic target continues to unfold, highlighting its relevance in contemporary biomedical research.
