Analytical Data
-
基因名
SLC9A3R2
- Application
-
别名
SLC9A3R2；TDF；Sex-determining region Y Protein
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q15599
-
表达区间
1-337aa
-
氨基酸序列
MAAPEPLRPR LCRLVRGEQG YGFHLHGEKG RRGQFIRRVE PGSPAEAAAL RAGDRLVEVN GVNVEGETHH QVVQRIKAVE GQTRLLVVDQ ETDEELRRRQ LTCTEEMAQR GLPPAHDPWE PKPDWAHTGS HSSEAGKKDV SGPLRELRPR LCHLRKGPQG YGFNLHSDKS RPGQYIRSVD PGSPAARSGL RAQDRLIEVN GQNVEGLRHA EVVASIKARE DEARLLVVDP ETDEHFKRLR VTPTEEHVEG PLPSPVTNGT SPAQLNGGSA CSSRSDLPGS DKDTEDGSAW KQDPFQESGL HLSPTAAEAK EKARAMRVNK RAPQMDWNRK REIFSNF
-
分子量
337 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SLC9A3R2, also known as Solute Carrier Family 9 Member A3 Regulator 2, is a member of the solute carrier family that plays a crucial role in cellular sodium and pH homeostasis. It functions primarily as a regulator of ion transport mechanisms within epithelial tissues. Research into SLC9A3R2 is particularly significant due to its involvement in various physiological processes and potential implications in diseases such as hypertension, heart failure, and certain kidney disorders. The protein's role in regulating Na+/H+ exchange may influence cellular signaling pathways, affecting calcium levels and numerous other intracellular processes. Moreover, alterations in SLC9A3R2 expression or function can be linked to pathological conditions, highlighting its potential as a therapeutic target. The recombinant expression of SLC9A3R2 provides an invaluable tool for studying its structure-function relationships and for developing specific inhibitors or activators that may modulate its activity. By investigating the protein's interactions, regulatory mechanisms, and impact on cellular environments, researchers aim to better understand its contributions to health and disease, paving the way for novel therapeutic strategies that leverage the modulation of this transport system.
