Analytical Data
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基因名
FOXM1
- Application
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别名
FOXM1；FKHL16；HFH11；MPP2；Forkhead box Protein M1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q08050
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表达区间
222-360aa
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氨基酸序列
PSRPSASWQNSVSERPPYSYMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETSANGKVSFWTIHPSANRYLTLDQVFKPLDPGSPQLPEHLESQQKRPNPELRRNMTIKTELP
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分子量
43.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
FOXM1, a member of the forkhead box (FOX) family of transcription factors, plays a crucial role in cell proliferation, differentiation, and survival. It is characteristically overexpressed in various cancers, making it a significant focus for cancer research. The protein is involved in critical cellular processes such as the cell cycle regulation, DNA damage repair, and the modulation of apoptosis, suggesting that its dysregulation can contribute to tumorigenesis. Research on recombinant FOXM1 proteins has gained prominence due to the necessity to understand its functional mechanisms and interactions within various signaling pathways. By producing FOXM1 as a recombinant protein, scientists can investigate its structural properties, post-translational modifications, and interactions with other cellular partners. Such studies not only deepen our understanding of FOXM1's role in cancer biology but also pave the way for potential therapeutic strategies aimed at targeting FOXM1 activity. Additionally, identifying small molecules or peptides that can inhibit FOXM1 may lead to novel cancer treatments, underscoring the importance of elucidating its functionality through recombinant protein studies.
