Analytical Data
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Gene name
HOXA3
- Application
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Alternative Names
HOXA3；HOX1E；Homeobox Protein Hox-A3
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O43365
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Expression Region
1-443aa
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AA Sequence
MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGGHPKAHELSEACLRTLSAPPSQPPSLGEPPLHPPPPQAAPPAPQPPQPAPQPPAPTPAAPPPPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTSSSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYEPQSPPPFSKPPQGTYGLPPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPHAHGLQGNGSYGTPHIQGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLGSGHHHGPGPGEPHPTYTDLTGHHPSQGRIQEAPKLTHL
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Molecular Weight
47.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HOXA3 is a member of the Homeobox gene family, which plays a crucial role in embryo development and the regulation of gene expression. As a transcription factor, HOXA3 is involved in various biological processes, including cell differentiation, proliferation, and apoptosis. Its expression patterns are significant during early development, particularly in the formation of the anterior-posterior axis and the development of structures such as the heart and limbs. Dysregulation of HOXA3 is associated with various developmental disorders and diseases, including cancer. Recent studies have focused on the recombinant production of HOXA3 protein to investigate its functional properties and potential therapeutic applications. This recombinant protein can be utilized to better understand the molecular mechanisms driven by HOXA3, opening avenues for targeted interventions in conditions where its function is impaired. By utilizing techniques like molecular cloning and protein expression systems, researchers aim to produce biologically active HOXA3 protein for in vitro studies, providing insights into its role in cellular processes and disease pathways. The findings from this research could lead to developments in regenerative medicine and targeted therapies, highlighting the importance of HOXA3 in developmental biology and disease mechanisms.
