Analytical Data
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基因名
NAA10
- Application
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别名
NAA10;ARD1;ARD1A;TE2;N-alpha-acetyltransferase 10
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P41227
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表达区间
1-235aa
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氨基酸序列
MAEVPPGPSS LLPPPAPPAP AAVEPRCPFP AGAALACCSE DEEDDEEHEG GGSRSPAGGE SATVAAKGHP CLRCPQPPQE QQQLNGLISP ELRHLRAAAS LKSKVLSVAE VAATTATPDG GPRATATKGA GVHSGERPPH SLSSNARTAV PSPVEAAAAS DPAAARNGLA EGTEQEEEEE DEQVRLLSSS LTADCSLRSP SGREVEPGED RTIRYVRYES ELQMPDIMRL ITKDLSEPYS IYTYRYFIHN WPQLCFLAMV GEECVGAIVC KLDMHKKMFR RGYIAMLAVD SKYRRNGIGT NLVKKAIYAM VEGDCDEVVL ETEITNKSAL KLYENLGFVR DKRLFRYYLN GVDALRLKLW LR
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分子量
29 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
NAA10, also known as NatA, is a crucial protein in the N-terminal acetylation process, which is an essential post-translational modification for numerous proteins in eukaryotic cells. This acetylation helps regulate protein stability, localization, and function, impacting various cellular processes such as cell cycle progression, signal transduction, and gene expression. Mutations or dysregulation of NAA10 have been associated with several diseases, including cancer and developmental disorders, highlighting its significance in maintaining cellular homeostasis. Research into recombinant NAA10 has gained momentum as scientists seek to understand its enzymatic mechanisms and broader biological implications. Generating recombinant NAA10 allows for detailed structural and functional studies that can uncover its role in pathophysiology and therapeutic potential. By employing techniques such as X-ray crystallography and enzymatic assays, researchers aim to elucidate the specific interactions and regulatory pathways involved in NAA10-mediated acetylation. Moreover, characterizing NAA10’s interactions with other cellular factors could pave the way for targeted drug design and innovative treatment strategies for NAA10-related diseases. Overall, the study of recombinant NAA10 is vital for advancing our understanding of post-translational modifications and their impact on cellular function and disease.
