Cat: PA2000-559DB

Recombinant Human NECTIN2 Protein,His

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Analytical Data

  • Gene name

    NECTIN2

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    NECTIN2;DNAM1;CD226 antigen

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q92692

  • Expression Region

    32-360aa

  • AA Sequence

    QDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPRASPRDVGPL

  • Molecular Weight

    36.58 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

NECTIN2, a member of the immunoglobulin superfamily, plays a crucial role in cell adhesion and communication. It is primarily expressed in various tissues, including the brain, placenta, and immune cells, where it contributes to the formation of adherens junctions and modulates immune responses. Due to its involvement in tumor progression and metastasis, NECTIN2 has garnered significant attention in cancer research. Elevated levels of NECTIN2 have been associated with several malignancies, making it a potential biomarker for cancer diagnosis and prognosis. Furthermore, its interaction with the herpes simplex virus (HSV) highlights its importance in viral infections, as NECTIN2 serves as a receptor facilitating viral entry into host cells. The development of NECTIN2 recombinant proteins offers valuable tools for studying its biological functions and interactions, enabling researchers to explore therapeutic avenues such as targeted cancer treatments and antiviral strategies. By elucidating NECTIN2’s role in various pathological contexts, researchers aim to harness its potential for improving disease detection and treatment outcomes, ultimately contributing to advancements in precision medicine and targeted therapies.

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