Analytical Data
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基因名
PPIC
- Application
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别名
PPIC；CYPC；Peptidyl-prolyl cis-trans isomerase C
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P45877
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表达区间
31-182aa
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氨基酸序列
MSDKIIHLTDDSFDTDVLKADGAILVDFWAEWCGPCKMIAPILDEIADEY QGKLTVAKLNIDQNPGTAPKYGIRGIPTLLLFKNGEVAATKVGALSKGQL KEFLDANLAGSGSGHMHHHHHHSSGLVPRGSGMKETAAAKFERQHMDSPD LGTDDDDKAMAKRGPSVTAKVFFDVRIGDKDVGRIVIGLFGKVVPKTVEN FVALATGEKGYGYKGSKFHRVIKDFMIQGGDITTGDGTGGVSIYGETFPD ENFKLKHYGIGWVSMANAGPDTNGSQFFITLTKPTWLDGKHVVFGKVIDG MTVVHSIELQATD
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分子量
34 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PPIC, or Peptidylprolyl isomerase C, is an essential enzyme that plays a crucial role in protein folding and chaperone activity in various biological processes. Its function is particularly important in the context of post-translational modifications, where it catalyzes the isomerization of proline residues in polypeptide chains, facilitating proper protein conformation and stability. Recent research highlights the significance of PPIC in cellular stress responses, protein quality control, and disease mechanisms, including cancer and neurodegenerative disorders. The study of recombinant PPIC proteins not only enhances our understanding of their biochemical properties but also provides insights into their potential therapeutic applications. Recombinant protein expression systems have advanced significantly, allowing for the high-yield production and purification of PPIC variants, which can be utilized for structural and functional analyses. By exploring the specific interactions and pathways involving PPIC, researchers aim to elucidate its role in cell biology and disease, paving the way for novel therapeutic strategies targeting protein misfolding and aggregation-related disorders. The ongoing exploration of PPIC's functionality underscores its promise as a pivotal component in the quest for understanding complex biological mechanisms and developing innovative treatments.
