Analytical Data
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基因名
KCTD11
- Application
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别名
KCTD11;C17orf36;REN;BTB/POZ domain-containing Protein KCTD11
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q693B1
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表达区间
1-232aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MLGAMFRAGT PMPPNLNSQG GGHYFIDRDG KAFRHILNFL RLGRLDLPRG YGETALLRAE ADFYQIRPLL DALRELEASQ GTPAPTAALL HADVDVSPRL VHFSARRGPH HYELSSVQVD TFRANLFCTD SECLGALRAR FGVASGDRAE GSPHFHLEWA PRPVELPEVE YGRLGLQPLW TGGPGERREV VGTPSFLEEV LRVALEHGFR LDSVFPDPED LLNSRSLRFV RH
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分子量
28 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KCTD11, a member of the potassium channel tetramerization domain-containing protein family, has garnered attention in recent years due to its potential roles in various physiological and pathological processes. Initially identified for its involvement in potassium channel regulation, KCTD11 is implicated in cellular signaling pathways and may influence developmental processes. Research has shown that KCTD11 can act as a modulator of protein interactions, affecting the activity of key signaling molecules. Abnormal expression or mutations in KCTD11 have been associated with several disorders, including neurodevelopmental issues and some forms of cancer. Consequently, the recombinant production of KCTD11 has become an important area of study, enabling researchers to investigate its structure, function, and interactions with other proteins in detail. By producing KCTD11 as a recombinant protein, scientists aim to explore its crystal structure, establish its binding characteristics, and develop assays to screen for potential therapeutic agents. The understanding gained from these studies could provide insights into the molecular mechanisms underlying diseases associated with KCTD11, paving the way for innovative treatment strategies and furthering our comprehension of potassium channel-related functions in health and disease.
