Analytical Data
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Gene name
MCM9
- Application
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Alternative Names
MCM9；C6orf61；MCMDC1；DNA helicase MCM9
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9NXL9
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Expression Region
1-391aa
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AA Sequence
MNSDQVTLVGQVFESYVSEYHKNDILLILKERDEDAHYPVVVNAMTLFETNMEIGEYFNMFPSEVLTIFDSALRRSALTILQSLSQPEAVSMKQNLHARISGLPVCPELVREHIPKTKDVGHFLSVTGTVIRTSLVKVLEFERDYMCNKCKHVFVIKADFEQYYTFCRPSSCPSLESCDSSKFTCLSGLSSSPTRCRDYQEIKIQEQVQRLSVGSIPRSMKVILEDDLVDSCKSGDDLTIYGIVMQRWKPFQQDVRCEVEIVLKANYIQVNNEQSSGIIMDEEVQKEFEDFWEYYKSDPFAGRNVILASLCPQVFGMYLVKLAVAMVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGLTVTAVK
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Molecular Weight
48.0 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MCM9, or Minichromosome Maintenance 9, is a crucial protein involved in the regulation of DNA replication and repair processes within the cell. As a member of the MCM family, MCM9 plays a significant role in the formation of the pre-replicative complex, which is essential for ensuring accurate DNA replication during the S phase of the cell cycle. Recent studies have indicated that MCM9 is not only vital for maintaining genomic integrity but also participates in various cellular responses to DNA damage, particularly in the context of homologous recombination repair mechanisms. Given its functional importance, understanding the molecular characteristics and interactions of MCM9 has become a focal point in cancer research, as alterations in its expression or activity can contribute to genomic instability and tumorigenesis. Additionally, MCM9 has been implicated in other cellular processes such as telomere maintenance and the regulation of transcription. Research into MCM9-related recombinant proteins has gained momentum, aiming to elucidate its structural properties and interaction networks, which could unveil potential therapeutic targets for cancer treatment and enhance our understanding of DNA repair pathways. The exploration of MCM9's role in DNA replication and repair could also provide insights into cellular aging and the mechanisms underlying various genetic disorders. Thus, the ongoing investigation into MCM9's functions and its related pathways remains a significant area of interest in molecular biology and genetics.
