Analytical Data
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Gene name
ITPK1
- Application
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Alternative Names
ITPK1;Inositol-tetrakisphosphate 1-kinase
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q13572
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Expression Region
1-414aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMQTFLK GKRVGYWLSE KKIKKLNFQA FAELCRKRGM EVVQLNLSRP IEEQGPLDVI IHKLTDVILE ADQNDSQSLE LVHRFQEYID AHPETIVLDP LPAIRTLLDR SKSYELIRKI EAYMEDDRIC SPPFMELTSL CGDDTMRLLE KNGLTFPFIC KTRVAHGTNS HEMAIVFNQE GLNAIQPPCV VQNFINHNAV LYKVFVVGES YTVVQRPSLK NFSAGTSDRE SIFFNSHNVS KPESSSVLTE LDKIEGVFER PSDEVIRELS RALRQALGVS LFGIDIIINN QTGQHAVIDI NAFPGYEGVS EFFTDLLNHI ATVLQGQSTA MAATGDVALL RHSKLLAEPA GGLVGERTCS ASPGCCGSMM GQDAPWKAEA DAGGTAKLPH QRLGCNAGVS PSFQQHCVAS LATKASSQ
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Molecular Weight
48 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ITPK1 (Inositol Trisphosphate 3-kinase B) is a member of the inositol phosphate kinase family, which plays a crucial role in various cellular processes by regulating inositol phosphate signaling pathways. Research on ITPK1 has garnered attention due to its significant involvement in cell proliferation, differentiation, and apoptosis, making it a potential target for therapeutic interventions in cancer and other diseases. Dysregulation of inositol phosphate signaling has been linked to various pathological conditions, highlighting the need for a deeper understanding of ITPK1's function within these pathways. Recombinant ITPK1 protein has been developed for biochemical studies and functional assays, enabling scientists to investigate its enzymatic activity, substrate specificity, and interactions with other signaling molecules. This approach not only aids in elucidating the molecular mechanisms governing ITPK1's role in cellular signaling but also paves the way for exploring its potential as a biomarker or therapeutic target in diseases such as cancer, neurodegenerative disorders, and metabolic syndromes. The ongoing research efforts aim to characterize the structural and functional properties of ITPK1, providing insights that could lead to innovative strategies for disease management by modulating inositol phosphate signaling pathways.
