Analytical Data
-
Gene name
ITLN1
- Application
-
Alternative Names
ITLN1;INTL;ITLN;LFR;Intelectin-1
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q8WWA0
-
Expression Region
17-313aa
-
AA Sequence
WSTD EANTYFKEWT CSSSPSLPRS CKEIKDECPS AFDGLYFLRT ENGVIYQTFC DMTSGGGGWT LVASVHENDM RGKCTVGDRW SSQQGSKAVY PEGDGNWANY NTFGSAEAAT SDDYKNPGYY DIQAKDLGIW HVPNKSPMQH WRNSSLLRYR TDTGFLQTLG HNLFGIYQKY PVKYGEGKCW TDNGPVIPVV YDFGDAQKTA SYYSPYGQRE FTAGFVQFRV FNNERAANAL CAGMRVTGCN TEHHCIGGGG YFPEASPQQC GDFSGFDWSG YGTHVGYSSS REITEAAVLL FYR
-
Molecular Weight
40 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ITLN1 (Intestinal Trefoil Factor 1) is a member of the trefoil factor family known for its role in mucosal protection and epithelial integrity in the gastrointestinal tract. Research has highlighted its significance in various biological processes, including cell proliferation, differentiation, and repair, particularly in response to injury or inflammation. The protein's expression is often upregulated in conditions such as inflammatory bowel disease (IBD) and colorectal cancer, suggesting a potential role in disease pathology. Scientists are intrigued by ITLN1's ability to stabilize mucin, enhance epithelial barrier function, and modulate immune responses, making it a candidate for therapeutic interventions in gastrointestinal disorders. Recent advancements in recombinant protein technology have enabled the production of ITLN1 for detailed functional studies, allowing researchers to explore its molecular mechanisms and therapeutic potential further. Understanding the structure-function relationship of ITLN1 and its interactions within the intestinal microenvironment may pave the way for novel diagnostic and therapeutic strategies aimed at improving mucosal health and managing inflammatory conditions. Thus, the study of ITLN1 is not only relevant for basic science but also holds promise for clinical applications in gastrointestinal diseases.
