Analytical Data
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Gene name
IPP1
- Application
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Alternative Names
PPP1R1A;IPP1;Protein phosphatase 1 regulatory subunit 1A
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q13522
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Expression Region
1-171aa
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AA Sequence
MEQDNSPRKIQFTVPLLEPHLDPEAAEQIRRRRPTPATLVLTSDQSSPEIDEDRIPNPHLKSTLAMSPRQRKKMTRITPTMKELQMMVEHHLGQQQQGEEPEGAAESTGTQESRPPGIPDTEVESRLGTSGTAKKTAECIPKTHERGSKEPSTKEPSTHIPPLDSKGANSV
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
IPP1, or Inositol Polyphosphate Phosphatase 1, is an essential enzyme that plays a key role in cellular signaling and metabolism by regulating inositol polyphosphate levels. This protein is crucial for various biological processes, including cell growth, differentiation, and apoptosis, making it a significant focus of research in cellular and molecular biology. Dysregulation of IPP1 has been implicated in several diseases, including cancer and metabolic disorders, highlighting the importance of understanding its functional mechanisms. Recent studies have aimed to elucidate the structural and functional characteristics of IPP1, particularly through the use of recombinant protein technology. By producing and characterizing IPP1 as a recombinant protein, researchers can investigate its enzymatic activity, binding interactions, and regulatory mechanisms in detail. Additionally, recombinant IPP1 can serve as a valuable tool for drug discovery, as it allows for high-throughput screening of potential inhibitors or activators that could modulate its activity in pathological conditions. As the understanding of IPP1's role in signaling pathways deepens, it may open new avenues for therapeutic interventions, ultimately leading to novel treatments for diseases associated with IPP1 dysregulation. The ongoing research into IPP1 underscores its significance in biochemistry and pharmacology, making it a promising target for future investigations aimed at improving human health.
