Analytical Data
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基因名
GPD1L
- Application
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别名
GPD1L；KIAA0089；Glycerol-3-phosphate dehydrogenase 1-like Protein
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8N335
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表达区间
1-351aa
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氨基酸序列
MGSSHHHHHHSSGLVPRGSHMAAAPLKVCIVGSGNWGSAVAKIIGNNVKK LQKFASTVKMWVFEETVNGRKLTDIINNDHENVKYLPGHKLPENVVAMSN LSEAVQDADLLVFVIPHQFIHRICDEITGRVPKKALGITLIKGIDEGPEG LKLISDIIREKMGIDISVLMGANIANEVAAEKFCETTIGSKVMENGLLFK ELLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLRCGDNTKAAVI RLGLMEMIAFARIFCKGQVSTATFLESCGVADLITTCYGGRNRRVAEAFA RTGKTIEELEKEMLNGQKLQGPQTSAEVYRILKQKGLLDKFPLFTAVYQI CYESRPVQEMLSCLQSHPEHT
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分子量
41 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GPD1L, or glycerol-3-phosphate dehydrogenase 1-like protein, has garnered significant attention in recent years due to its critical role in cellular metabolism and its implications in various health conditions. Functioning primarily in the glycerol phosphate shuttle, GPD1L is integral in mitochondrial function and energy production, particularly in tissues with high energy demands, such as the heart and skeletal muscle. Mutations in the GPD1L gene have been implicated in inherited cardiac disorders, including arrhythmogenic right ventricular cardiomyopathy and familial dilated cardiomyopathy, highlighting its potential as a biomarker for cardiovascular diseases. Research into GPD1L has expanded beyond basic metabolic studies to include its involvement in oxidative stress response and lipid metabolism, suggesting a multifaceted role in both health and disease. As such, recombinant GPD1L proteins have been developed for various experimental applications, offering insights into its enzymatic activity and substrate interactions. The study of GPD1L not only enhances our understanding of metabolic diseases but also paves the way for potential therapeutic strategies aimed at modulating its activity in the context of cardiac dysfunction.
