Analytical Data
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Gene name
CCDC6
- Application
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Alternative Names
CCDC6；D10S170；TST1；Coiled-coil domain-containing Protein 6
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q16204
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Expression Region
2-474aa
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AA Sequence
ADSASESDTDGAGGNSSSSAAMQSSCSSTSGGGGGGGGGGGGGKSGGIVISPFRLEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESESSLEMDDERYFNEMSAQGLRPRTVSSPIPYTPSPSSSRPISPGLSYASHTVGFTPPTSLTRAGMSYYNSPGLHVQHMGTSHGITRPSPRRSNSPDKFKRPTPPPSPNTQTPVQPPPPPPPPPMQPTVPSAATSQPTPSQHSAHTSSQP
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Molecular Weight
60.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CCDC6 (Coiled-Coil Domain Containing 6) is a protein that has garnered attention due to its potential implications in various biological processes and diseases. It plays a significant role in cellular functions such as proliferation, apoptosis, and differentiation. Research has indicated that CCDC6 is involved in the response to DNA damage and the regulation of cellular stress, making it a key player in maintaining genomic stability. Furthermore, mutations and dysregulation of CCDC6 expression have been associated with several types of cancer, including thyroid tumors, where it may function as a tumor suppressor gene. Given its involvement in cancer biology, CCDC6 has become a focus for researchers seeking to understand its mechanistic role in tumorigenesis and to explore its potential as a therapeutic target. The development and characterization of recombinant CCDC6 protein enable scientists to study its structure-function relationships, protein interactions, and biological activities in greater detail. Such studies not only deepen our understanding of CCDC6's role in health and disease but also open avenues for novel cancer therapies that exploit the pathways associated with this protein. The ongoing research into CCDC6 and its recombinant forms is promising, providing valuable insights that could lead to advancements in cancer treatment and the development of biomarkers for diagnosis and prognosis.
