Analytical Data
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基因名
MRTFA
- Application
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别名
MRTFA；KIAA1438；MAL；MKL1；Myocardin-related transcription factor A
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q969V6
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表达区间
400-500aa
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氨基酸序列
LHKAGEVVVAFPAARLSTGPALVAAGLAPAEVVVATVASSGVVKFGSTGSTPPVSPTPSERSLLSTGDENSTPGDTFGEMVTSPLTQLTLQASPLQILVKE
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分子量
25.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MRTFA (Myocardin-related transcription factor A) is a member of the MRTF family of transcription regulators that play a crucial role in various cellular processes, including muscle cell differentiation, proliferation, and the regulation of smooth muscle contraction. The study of MRTFA is particularly relevant due to its involvement in pathological conditions such as vascular diseases and cancer. It is known to interact with the actin cytoskeleton, thereby influencing gene expression in response to mechanical and biochemical stimuli. Understanding the structure and function of MRTFA and its signaling pathways can provide insight into the mechanisms underlying cardiovascular diseases and other disorders linked to smooth muscle regulation. The characterization of MRTFA recombinant proteins has become an essential tool in exploring its biological functions and potential as a therapeutic target. Through various biochemical and biophysical techniques, researchers aim to elucidate the molecular mechanisms by which MRTFA modulates transcriptional activity and cellular responses, paving the way for novel interventions in diseases where MRTFA is dysregulated.
