Analytical Data
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基因名
HOXB1
- Application
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别名
HCFP3; Homeo box 2I; Homeo box B1; Homeobox 2I; Homeobox B1; Homeobox protein Hox B1; Homeobox protein Hox-2I; Homeobox protein Hox-B1; Homeobox protein HoxB1; Homeobox2I; HomeoboxB1; HOX 2; Hox 2.9; HOX 2I; HOX B1; HOX2; Hox2.9; HOX2I; HOXB 1; HOXB1; HOXB1 protein; HXB1_HUMAN; MGC116843; MGC116844; MGC116845
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P14653
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表达区间
1-301aa
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氨基酸序列
MDYNRMNSFL EYPLCNRGPS AYSAHSAPTS FPPSSAQAVD SYASEGRYGG GLSSPAFQQN SGYPAQQPPS TLGVPFPSSA PSGYAPAACS PSYGPSQYYP LGQSEGDGGY FHPSSYGAQL GGLSDGYGAG GAGPGPYPPQ HPPYGNEQTA SFAPAYADLL SEDKETPCPS EPNTPTARTF DWMKVKRNPP KTAKVSEPGL GSPSGLRTNF TTRQLTELEK EFHFNKYLSR ARRVEIAATL ELNETQVKIW FQNRRMKQKK REREEGRVPP APPGCPKEAA GDASDQSTCT SPEASPSSVT S
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分子量
32.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HOXB1, a member of the homeobox gene family, plays a critical role in embryonic development, particularly in the formation of the hindbrain and the patterning of the nervous system. Its expression is tightly regulated during early development, and any dysregulation can lead to congenital abnormalities and neurological disorders. Recent studies have highlighted the importance of HOXB1 in various cellular processes, including cell differentiation, proliferation, and apoptosis. Given its significant biological functions, researchers have turned to recombinant protein technology to produce HOXB1 in a controlled laboratory setting. This approach allows for detailed study of HOXB1's structure-function relationships, interactions with other proteins, and its role in developmental pathways. By generating recombinant HOXB1, scientists aim to uncover the molecular mechanisms underlying its function and to assess its potential implications in regenerative medicine and developmental therapies. Understanding HOXB1's role could pave the way for novel therapeutic strategies targeting HOXB1-related conditions, making this research area highly relevant and promising in both basic and applied sciences. As the development of efficient recombinant protein expression systems continues to improve, the study of HOXB1 and its therapeutic potentials remains a fertile ground for future investigations.
