Analytical Data
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基因名
GIMAP6
- Application
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别名
GIMAP6；IAN2；IAN6；IMAP3;GTPase IMAP family member 6
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6P9H5
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表达区间
1-292aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSMEEEEYE QIPQENPPEE LSQDPVLELS GGLREKEQKT PRRLRLILMG KTGSGKSATG NSILGRDVFE SKLSTRPVTK TSQRRSREWA GKELEVIDTP NILSPQVSPE VADAICQAIV LSAPGPHAVL LVTQLGRFTD EDQQVVRRLQ EVFGVGVLGH TILVFTRKED LAGGSLEDYV RETNNQALAW LDVTLARRHC GFNNRAQGEE QEAQLRELME KVEAIMWENE GDYYSNKAYQ YTQQNFRLKE LQERQVSQGQ GSEDVPGEES WLEGLSQIQK ESEEAHRCLL GKADL
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分子量
35 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GIMAP6 (GTPase of immunity-associated protein 6) is a member of the GIMAP family of GTPases, which are involved in various immune responses and cellular functions. Research has shown that GIMAP6 plays a significant role in lymphocyte development and apoptosis, particularly in T cells. Its expression is notably elevated in immune tissues, indicating its potential involvement in immune regulation. Dysregulation of GIMAP6 has been linked to autoimmune diseases and lymphoid malignancies, which raises interest in understanding its mechanistic roles further. Studies have utilized recombinant GIMAP6 proteins to investigate their biochemical properties, signaling pathways, and interactions with other proteins. By producing and characterizing GIMAP6 in its recombinant form, researchers aim to elucidate its structure-function relationship and how it contributes to the immune system’s integrity. This knowledge could pave the way for novel therapeutic approaches targeting GIMAP6 in immune-related conditions. The ongoing investigation of GIMAP6 signifies its importance in immunology and its potential implications for developing targeted therapies in the context of autoimmune disorders and cancer.
