Analytical Data
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基因名
MIP1b
- Application
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别名
MIP1b;LAG1;MIP1B;SCYA4;C-C motif chemokine 4
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P13236
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表达区间
24-92aa
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氨基酸序列
APMGSDPPTACCFSYTARKLPRNFVVDYYETSSLCSQPAVVFQTKRGKQV CADPSESWVQEYVYDLELN
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分子量
8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MIP1b (Macrophage Inflammatory Protein 1 beta) is a chemokine that plays a crucial role in the immune response, particularly in the recruitment and activation of immune cells such as macrophages and T cells. Understanding the functions and mechanisms of MIP1b is significant for developing therapeutic approaches to various inflammatory diseases, autoimmune disorders, and cancer. Recent studies have revealed that MIP1b not only participates in normal immune regulation but also influences the progression of diseases by modulating inflammatory responses. Researchers are interested in producing recombinant MIP1b proteins to study its biological activities and interactions with receptors. These proteins can facilitate the exploration of how MIP1b functions in both physiological and pathological conditions, enabling the identification of potential therapeutic targets. Additionally, the recombinant MIP1b can be utilized in the development of vaccines and immunotherapies, offering hope for improved treatments for conditions characterized by dysregulated immune responses. The exploration of MIP1b’s role in chronic inflammation and tumor microenvironments may provide insights into novel strategies aimed at harnessing the immune system to combat diseases. Overall, the research on recombinant MIP1b proteins holds promise for advancing our understanding of immune mechanisms and developing innovative therapeutic approaches.












