Analytical Data
-
Gene name
MIP1a
- Application
-
Alternative Names
MIP1a；G0S19-1；MIP1A；SCYA3；C-C motif chemokine 3
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
P10147
-
Expression Region
23-92aa
-
AA Sequence
ASLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPGV IFLTKRSRQV CADPSEEWVQ KYVSDLELSA
-
Molecular Weight
7.8 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MIP1alpha, also known as macrophage inflammatory protein 1-alpha (CCL3), is a chemokine that plays a crucial role in the immune response by attracting immune cells, particularly monocytes and T cells, to sites of inflammation. Its involvement in various pathological conditions, such as autoimmune diseases, infectious diseases, and cancer, has driven research interest in the therapeutic potential of MIP1alpha. The recombinant production of MIP1alpha allows for the exploration of its biological activities and mechanisms in a controlled environment. By studying the structure-function relationship of MIP1alpha, researchers aim to uncover its role in cell signaling and migration, providing insights into its potential applications in immunotherapy and inflammation management. Additionally, recombinant MIP1alpha can serve as a valuable tool for developing novel diagnostic and therapeutic strategies, enhancing our understanding of the immune landscape in various diseases. The continued investigation of MIP1alpha and its recombinant forms holds promise for advancing our knowledge of immune regulation and developing targeted treatments for inflammatory conditions.
