Analytical Data
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基因名
MIP1a
- Application
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别名
MIP1a；G0S19-1；MIP1A；SCYA3；C-C motif chemokine 3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P10147
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表达区间
23-92aa
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氨基酸序列
ASLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPGV IFLTKRSRQV CADPSEEWVQ KYVSDLELSA
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分子量
7.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MIP1alpha, also known as macrophage inflammatory protein 1-alpha (CCL3), is a chemokine that plays a crucial role in the immune response by attracting immune cells, particularly monocytes and T cells, to sites of inflammation. Its involvement in various pathological conditions, such as autoimmune diseases, infectious diseases, and cancer, has driven research interest in the therapeutic potential of MIP1alpha. The recombinant production of MIP1alpha allows for the exploration of its biological activities and mechanisms in a controlled environment. By studying the structure-function relationship of MIP1alpha, researchers aim to uncover its role in cell signaling and migration, providing insights into its potential applications in immunotherapy and inflammation management. Additionally, recombinant MIP1alpha can serve as a valuable tool for developing novel diagnostic and therapeutic strategies, enhancing our understanding of the immune landscape in various diseases. The continued investigation of MIP1alpha and its recombinant forms holds promise for advancing our knowledge of immune regulation and developing targeted treatments for inflammatory conditions.
