Analytical Data
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基因名
HELT
- Application
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别名
HELT; Hairy and enhancer of split-related protein HELT; HES/HEY-like transcription factor
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
A6NFD8
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表达区间
1-327aa
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氨基酸序列
MSDKLKERKVSRLSPNGTCALVVEASDSPTRHLGGPMAGKCPHGTLSVEESRVRTPVSHKVIEKRRRDRINRCLNELGKTVPMALAKQGEPQEALAQIRSRVRSLVLSSATVPDQQALGRCEGPFLLLQSSGKLEKAEILEMTVQYLRALHSADFPRGREKAELLAEFANYFHYGYHECMKNLVHYLTTVERMETKDTKYARILAFLQSKARLGAEPAFPPLGSLPEPDFSYQLHPAGPEFAGHSPGEAAVFPQGSGAGPFPWPPGAARSPALPYLPSAPVPLASPAQQHSPFLTPVQGLDRHYLNLIGHAHPNALNLHTPQHPPVL
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分子量
36 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HELT, or hematopoietic and lymphoid tissue protein, is a notable protein involved in various biological processes, particularly within the immune system. The study of HELT-recombinant proteins has gained momentum due to its potential implications in understanding hematopoiesis, lymphocyte development, and immune responses. Previous research has highlighted HELT’s role in regulating gene expression and its interaction with other transcription factors, which are crucial for normal immune function and the differentiation of hematopoietic cells. Moreover, abnormalities in HELT expression have been linked to certain hematological disorders, thus emphasizing the importance of understanding its molecular mechanisms. The generation of HELT-recombinant proteins allows for detailed biochemical characterization and functional studies, enabling researchers to dissect its role in cellular signaling pathways and its potential as a therapeutic target. Continued investigation into HELT could provide insights into novel approaches for treating immune-related diseases and improving our understanding of the fundamental processes governing blood cell formation and immunity. With advancements in protein engineering and production technologies, the availability of HELT-recombinant proteins can significantly enhance experimental approaches in both basic and applied biomedical research, paving the way for innovative strategies in immunotherapy and regenerative medicine.
