Analytical Data
-
基因名
ROR2
- Application
-
别名
ROR2；NTRKR2；Tyrosine-Protein kinase transmembrane receptor ROR2
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q01974
-
表达区间
34-403aa
-
氨基酸序列
EVEVLDPNDPLGPLDGQDGPIPTLKGYFLNFLEPVNNITIVQGQTAILHC KVAGNPPPNVRWLKNDAPVVQEPRRIIIRKTEYGSRLRIQDLDTTDTGYY QCVATNGMKTITATGVLFVRLGPTHSPNHNFQDDYHEDGFCQPYRGIACA RFIGNRTIYVDSLQMQGEIENRITAAFTMIGTSTHLSDQCSQFAIPSFCH FVFPLCDARSRTPKPRELCRDECEVLESDLCRQEYTIARSNPLILMRLQL PKCEALPMPESPDAANCMRIGIPAERLGRYHQCYNGSGMDYRGTASTTKS GHQCQPWALQHPHSHHLSSTDFPELGGGHAYCRNPGGQMEGPWCFTQNKN VRMELCDVPSCSPRDSSKMG
-
分子量
68 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ROR2, a member of the receptor tyrosine kinase-like orphan receptor family, plays a crucial role in various physiological and pathological processes, including skeletal development and tumor progression. It is predominantly expressed in skeletal tissues and is essential for proper limb formation during embryonic development. Mutations in the ROR2 gene are linked to bone disorders such as Robinow syndrome, characterized by skeletal dysplasia and other developmental abnormalities. Additionally, ROR2 has been implicated in cancer biology, where its expression levels can influence tumor growth and metastasis. Research on the recombinant protein of ROR2 has gained momentum due to its potential as a therapeutic target. By generating ROR2 recombinant proteins, scientists aim to elucidate its biological functions and signaling pathways, which could lead to innovative treatments for diseases associated with ROR2 dysregulation. Understanding the structure-function relationship of ROR2 at the protein level can also facilitate the design of novel inhibitors or modulators that could intervene in its signaling mechanisms. Thus, the study of ROR2 recombinant protein is pivotal not only for basic research but also for developing strategies to combat ROR2-related disorders and malignancies.
