Analytical Data
-
基因名
EPX
- Application
-
别名
EPX；EPER；EPO；EPP；Eosinophil peroxidase
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
P11678
-
表达区间
1-715aa
-
氨基酸序列
MHLLPALAGVLATLVLAQPCEGTDPASPGAVETSVLRDCIAEAKLLVDAA YNWTQKSIKQRLRSGSASPMDLLSYFKQPVAATRTVVRAADYMHVALGLL EEKLQPQRSGPFNVTDVLTEPQLRLLSQASGCALRDQAERCSDKYRTITG RCNNKRRPLLGASNQALARWLPAEYEDGLSLPFGWTPSRRRNGFLLPLVR AVSNQIVRFPNERLTSDRGRALMFMQWGQFIDHDLDFSPESPARVAFTAG VDCERTCAQLPPCFPIKIPPNDPRIKNQRDCIPFFRSAPSCPQNKNRVRN QINALTSFVDASMVYGSEVSLSLRLRNRTNYLGLLAINQRFQDNGRALLP FDNLHDDPCLLTNRSARIPCFLAGDTRSTETPKLAAMHTLFMREHNRLAT ELRRLNPRWNGDKLYNEARKIMGAMVQIITYRDFLPLVLGKARARRTLGH YRGYCSNVDPRVANVFTLAFRFGHTMLQPFMFRLDSQYRASAPNSHVPLS SAFFASWRIVYEGGIDPILRGLMATPAKLNRQDAMLVDELRDRLFRQVRR IGLDLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRVLKNQDLAR KFLNLYGTPDNIDIWIGAIAEPLLPGARVGPLLACLFENQFRRARDGDRF WWQKRGVFTKRQRKALSRISLSRIICDNTGITTVSRDIFRANIYPRGFVN CSRIPRLNLSAWRGT
-
分子量
106 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
EPX (Eosinophil Peroxidase) is a heme-containing enzyme primarily found in eosinophils, a type of white blood cell involved in the immune response, particularly in combating parasitic infections and mediating allergic reactions. Research into EPX has gained traction due to its dual role as a biomarker for eosinophilic disorders and its potential involvement in various inflammatory diseases. Investigations into the structure and function of EPX have revealed its catalytic properties, which contribute to the generation of reactive oxygen species and the oxidative damage of pathogens. Moreover, the enzyme's involvement in tissue remodeling and its potential to exacerbate conditions like asthma and chronic rhinosinusitis have made it a target for therapeutic intervention. Recent studies have emphasized the importance of understanding the molecular mechanisms underlying EPX activity and its regulation within the eosinophil compartment. By exploring its interactions with other proteins and signaling pathways, researchers aim to uncover novel strategies for modulating EPX function, which could lead to the development of innovative treatments for eosinophil-associated diseases. As such, EPX serves not only as a critical participant in immune responses but also as a focal point in the quest for more effective management of allergic and inflammatory disorders.
