Analytical Data
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基因名
CCL4L1
- Application
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别名
CCL4L1；CCL4L；LAG1；SCYA4L1；C-C motif chemokine 4-like
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8NHW4
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表达区间
24 -92aa
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氨基酸序列
MGSSHHHHHHSSGLVPRGSHMGSHMAPMGSDPPTACCFSYTARKLPRNFV VDYYETSSLCSQPAVVFQTKRGKQVCADPSESWVQEYVYDLELN
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分子量
11 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CCL4L1, a member of the C-C motif chemokine family, plays a crucial role in immune responses and inflammatory processes. It is primarily involved in recruiting monocytes and lymphocytes to sites of inflammation, thus contributing to the pathogenesis of various diseases, including autoimmune disorders and infections. Research has highlighted its significance in conditions like HIV infection, where it can influence viral replication and persistence. Additionally, CCL4L1 and its receptors exhibit potential therapeutic targets for modulating immune responses, making them intriguing for drug development. Studies have focused on the recombinant expression of CCL4L1 to facilitate the exploration of its functional properties and its interaction with immune cells. Understanding the structure-function relationship of CCL4L1 at the molecular level could pave the way for innovative treatments targeting immune dysregulation. Expanding our knowledge of CCL4L1 may offer insights into more effective therapeutic strategies for various immune-related diseases, emphasizing the importance of continued research in this area.
