Analytical Data
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基因名
CCL26
- Application
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别名
CCL26;SCYA26;C-C motif chemokine 26
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y258
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表达区间
24-94aa
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氨基酸序列
TRGSDISKTC CFQYSHKPLP WTWVRSYEFT SNSCSQRAVI FTTKRGKKVC THPRKKWVQK YISLLKTPKQ L
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分子量
8.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CCL26, also known as eotaxin-3, is a chemokine primarily involved in the recruitment of eosinophils and other immune cells to sites of inflammation, playing a critical role in allergic responses and asthma pathogenesis. It is produced by various cell types, including epithelial cells, and has been implicated in several chronic inflammatory diseases. Research indicates that elevated levels of CCL26 are associated with conditions such as asthma, rhinitis, and atopic dermatitis, highlighting its potential as a biomarker for these diseases. The study of CCL26 has garnered significant interest due to its role in mediating the Th2-type immune response and its involvement in tissue remodeling and fibrosis. Understanding the mechanisms of CCL26 action and signaling pathways could unveil new therapeutic targets for the treatment of allergic diseases and other related disorders. Given the importance of eosinophil infiltration in chronic inflammation, recombinant CCL26 protein studies aim to elucidate its functions in vivo and in vitro, providing insights into potential interventions. Furthermore, the potential use of CCL26 in developing novel therapeutic strategies or targeted treatments could advance the current paradigm of managing allergic diseases, underscoring the need for continued research in this area.












