Analytical Data
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基因名
CCL25
- Application
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别名
CCL25;SCYA25;TECK;C-C motif chemokine 25
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O15444
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表达区间
24-150aa
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氨基酸序列
M+QGVFEDCCL AYHYPIGWAV LRRAWTYRIQ EVSGSCNLPA AIFYLPKRHR KVCGNPKSRE VQRAMKLLDA RNKVFAKLHH NTQTFQAGPH AVKKLSSGNS KLSSSKFSNP ISSSKRNVSL LISANSGL
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分子量
14.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CCL25, also known as thymus-expressed chemokine (TECK), is a human chemokine that plays a crucial role in the migration and localization of T lymphocytes, particularly in the mucosal immune response. It is predominantly expressed in the thymus and intestinal tissues, where it facilitates the homing of naive T cells to gut-associated lymphoid tissues (GALT). The study of CCL25 has garnered significant interest due to its potential applications in understanding autoimmune diseases, inflammatory bowel disease, and various cancers, as it is involved in the recruitment of immune cells to sites of inflammation. Recent advancements in recombinant protein technology have enabled the production of CCL25 in large quantities, allowing researchers to investigate its structural and functional properties. This recombinant protein serves as a valuable tool in elucidating the signaling pathways and biological mechanisms underlying T cell trafficking. Moreover, CCL25's role as a therapeutic target is being explored, with the potential to develop novel treatments that modulate immune responses in various pathological conditions. Understanding CCL25's interactions with its receptors and its downstream signaling pathways could pave the way for innovative therapeutic approaches in immunology and oncology. As such, research on CCL25 recombinant proteins continues to be a significant area of interest, offering insights into the complexities of immune system regulation and potential intervention strategies for immune-mediated diseases.












